How does Metformin work?

Metformin is usually the first line of defense for treating Type 2 diabetes because it is highly effective, affordable, and safe. It works primarily in your liver. Throughout the day, your liver acts as a glucose warehouse, releasing stored sugar into your bloodstream to keep you energized. Metformin commands the liver to drastically reduce the amount of glucose it pumps out. Secondly, it helps improve insulin sensitivity in your muscle cells, allowing them to absorb the sugar that is circulating in your blood more effectively. Because it doesn't stimulate the pancreas to pump out more insulin, Metformin rarely causes dangerous low blood sugars (hypoglycemia). The most common side effects are gastrointestinal: nausea, stomach cramps, and diarrhea. To minimize these issues, you should always take Metformin exactly in the middle of a large meal, never on an empty stomach. Furthermore, ask your doctor for the extended-release (ER) version of the medication, which breaks down much slower in your digestive tract and eliminates the stomach distress for the vast majority of patients.